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Credits: 1.0 CME / 1.0 CNE
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Expires: 5/2014
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As part of the 2012 CME/CE NetWorkShops™ Webinar series, hemophilia experts Miguel Escobar, MD; Patrick Fogarty, MD; Mark Reding, MD; Tammuella Singleton, MD; and Leonard Valentino, MD, provide their insights on current issues and practices in hemophilia care.
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April 17 is World Hemophilia Day, an annual event started by the World Federation of Hemophilia (WFH) to unite the global bleeding disorders community in raising awareness about hemophilia and other related bleeding disorders. This year’s event has special significance because it marks 50 years of advancing the cause for the treatment and care of all individuals with hemophilia and rare bleeding disorders.
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Credits: 1.0 CME / 1.0 CNE
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Expires: 11/2013
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This year’s CME/CE NetWorkShopsTM Webinar series features leaders in hemophilia care who offer their insights on findings from national and international meetings that took place in 2012. Miguel Escobar, MD; Thomas E. Howard, MD, PhD; Benjamin Kim, MD, MPhil; Thomas Loew, MD; Ellis Neufeld, MD, PhD; Doris Quon, MD, PhD; and Tammuella Chrisentery Singleton, MD, discuss new challenges in hemophilia, inhibitor risk development, ITI, treatment adherence, cost, PT and elective orthopedic surgery, and pain management.
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In this learning activity, noted Blood CME Center faculty David Green, MD, PhD; Maureane Hoffman, MD, PhD; and Flora Peyvandi, MD, PhD share their perspectives on the rare coagulation deficiencies in a discussion that addresses the physiology of coagulation and the role of clotting factors, as well as the epidemiology, clinical presentation, and treatment of RBDs.
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Credits: 1.0 CME / 1.0 CNE
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Expires: 12/2013
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This case-focused learning activity brings together a hemophilia expert and a rheumatologist to discuss the musculoskeletal complications of hemophilia and related comorbidities in the aging patient. Patrick F. Fogarty, MD, and Jeffrey R. Lisse, MD, share information on hemophilic arthropathy and the differentiating features of other diseases with musculoskeletal presenting characteristics, such as gout and osteoporosis.
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Credits: 0.5 CME / 0.4 CNE
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Expires: 12/2013
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In this interactive learning activity featuring hemophilia expert Mark T. Reding, MD, clinical questions are posed with follow-up discussion that focuses on the perioperative management of hemophilia patients with inhibitors.
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Credits: 0.75 CME / 0.7 CNE
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Expires: 12/2013
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In this clinical consult, 6 hemophilia experts bring awareness of the most recent scientific findings and empirical data in the field of rare bleeding disorders (RBDs). They discuss barriers to care, genetics and prenatal counseling, new high-tech testing, the clinical phenotype of FVII deficiency, treatment advances, and RBD registries. This activity presents insights gleaned from the 2012 symposium of the American Society of Pediatric Hematology/Oncology.
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Credits: 0.5 CME / 0.5 CNE
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Expires: 12/2013
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Patients with hemophilia may have age-related comorbidities similar to the general population. Here, Miguel A. Escobar, MD, and Tammuella C. Singleton, MD, discuss 2 hemophiliac patient cases: a child presenting to the ED with head trauma and a 62-year-old who needs cardiac surgery. They offer diagnostic and long-term management insight, highlighting a comprehensive, multidisciplinary team approach to treatment, especially when outcomes are complicated by comorbid conditions.
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Credits: 0.5 CME / 0.4 CNE
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Expires: 11/2013
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Patients with hemophilia may have other conditions common to the general population, but diagnosis and treatment can be complicated by the bleeding disorder. In this activity, Miguel Escobar, MD, and Gabriel Aisenberg, MD, present 2 case scenarios and discuss how to approach testing and treatment accommodations in comorbid diseases, emphasizing the cooperation of the internist and hemotologist to improve outcomes in the aging hemophilia patient.
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Credits: 1.0 CME / 1.0 CNE
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Expires: 11/2013
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With the advent of effective and safe therapy for both hemophilia A and B, the outlook for patients with the disorder has been improved radically, and many are able to live as normal a life as possible. However, these benefits rely on patients’ optimal adherence to treatment. In this case-based learning activity, hemophilia clinicians Patrick Fogarty, MD, and Susan Karp, RN, MS, discuss the major barriers to adherence for patients and address strategies that healthcare providers can employ to assist patients in adhering to treatment to improve quality of life and outcomes.
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Credits: 0.5 CME / 0.4 CNE
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Expires: 11/2013
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This Point of Care Challenge provides expert opinion discussion of questions that may arise during an encounter with a hemophilia patient with inhibitors who presents with an acute bleeding episode. In this presentation, Leonard Valentino, MD, offers clinical insights into the multidisciplinary management of patients with hemophilia and inhibitors to improve long-term outcomes, reduce complications, and minimize joint damage. He discusses immune tolerance induction protocols and prophylaxis options, as well as physical therapy, pain control, and counseling points.
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Credits: 0.5 CME / 0.4 CNE
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Expires: 10/2013
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Recognition of acquired hemophilia (AHA) presents a clinical challenge, given the rarity of the condition and the potential for confusion with more common causes of bleeding. Prompt diagnosis is central to patient prognosis. In this presentation, Aryeh Shander, MD, offers his clinical insights into the clinical differentiation of AHA from congenital hemophilia and the appropriate treatment options.
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Credits: 1.0 CME / 1.0 CNE
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Expires: 10/2013
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Prior to the Blood CME Center symposium held during the 25th Annual Meeting of the American Society of Pediatric Hematology/Oncology (ASPHO), presenting faculty shared their expertise about the direction they would like to see research take to enhance clinician understanding of rare bleeding disorders (RBDs), regional and cultural barriers to be overcome, and key takeaway messages.
Select the questions about RBDs that were posed to the panel and receive answers from the experts in this educational activity.
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Credits: 1.75 CME / 1.7 CNE
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Expires: 10/2013
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Rare bleeding disorders (RBDs), as their name suggests, are infrequently encountered in clinical practice. Now, however, clinicians can get the latest information on the subject by watching proceedings of a Blood CME Center symposium, titled Rare Bleeding Disorders: Clinical Presentation, Diagnosis, and Current Therapeutic Interventions, that was recently held in conjunction with the 25th Annual Meeting of the American Society of Pediatric Hematology and Oncology.
This symposium brought together 6 RBD experts: Suchitra S. Acharya, MD; Manuel D. Carcao, MD, FRCPC, MSc; Marilyn J. Manco-Johnson, MD; Guglielmo Mariani, MD; Flora Peyvandi, MD, PhD; and Amy D. Shapiro, MD. The renowned faculty shared their expert opinion and offered the latest information on RBDs based on their involvement in national and international registries.
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Credits: 0.25 CME / 0.2 ANCC
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Expires: 9/2013
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Blood CME Center faculty discusses treatment approaches for pediatric patients with hemophilia. In a videotaped panel discussion, hemophilia experts Patrick Fogarty, MD; Tammuella Chrisentery Singleton, MD; Susan Karp, RN, MS; and Samir Mehta, MD, representing various perspectives of the hemophilia treatment center team, discuss prophylactic bypassing therapy in pediatric inhibitor patients to avoid musculoskeletal complications.
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Credits: 0.25 CME / 0.2 ANCC
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Expires: 9/2013
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Blood CME Center faculty discusses treatment approaches for adult patients with hemophilia and age-related comorbidities. In a videotaped panel discussion, hemophilia experts Patrick Fogarty, MD; Tammuella Chrisentery Singleton, MD; Susan Karp, RN, MS; and Samir Mehta, MD, representing various perspectives of the hemophilia treatment center team, discuss the impact of acute and chronic pain in patients with hemophilia.
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Credits: 0.25 CME / 0.2 CNE
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Expires: 9/2013
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Blood CME Center faculty discusses treatment approaches for adult patients with hemophilia and age-related comorbidities. In a videotaped panel discussion, hemophilia experts Patrick Fogarty, MD; Tammuella Chrisentery Singleton, MD; Susan Karp, RN, MS; and Samir Mehta, MD, representing various perspectives of the hemophilia treatment center team, discuss prophylactic bypassing therapy in adult hemophilia patients who undergo orthopedic surgery.
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Credits: 0.25 CME / 0.2 CNE
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Expires: 8/2013
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Watch a videotaped panel discussion featuring Blood CME Center faculty members addressing the management of musculoskeletal complications in pediatric patients with hemophilia. Bleeding disorders expert Patrick Fogarty, MD, moderates an exchange among Tammuella Chrisentery Singleton, MD; Angela Forsyth, PT, DPT; Susan Karp, RN, MS; and Samir Mehta, MD; each offering a unique perspective as members of the hemophilia care team. Specific issues covered include mild hemophilia with inhibitors, ways to educate the pediatric patient and his family, and treatment strategies, including prophylaxis with the bypassing agents.
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Credits: 0.5 CME / 0.4 CNE
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Expires: 7/2013
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Blood CME Center faculty members participate in a case-based educational activity that specifically addresses treatment approaches for adult patients with hemophilia and age-related comorbidities. In a videotaped panel discussion moderated by hemophilia expert Patrick Fogarty, MD, colleagues Tammuella Chrisentery Singleton, MD; Angela Forsyth, PT, DPT; Susan Karp, RN, MS; and Samir Mehta, MD; representing various perspectives of the hemophilia treatment center team, discuss issues central to the management of musculoskeletal complications in adult patients with hemophilia. Specific topics covered include surgical options and considerations, physical therapy regimens for patients with or without inhibitors, and coordination of care for improved outcomes.
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Angela Forsyth, PT, DPT, discusses the distinguishing aspects of physical therapy in patients with hemophilia and hemophilia with inhibitors, while offering advice to clinicians who may not routinely treat this patient population. As part of the activity, Dr. Forsyth conducts a physical assessment of the knee joint, focusing on swelling, crepitus on motion, and flexion and extension loss.
The faculty reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this activity:
Consulting Fees: Novo Nordisk Inc.; Fees for Non-CME Services Received Directly From a Commercial Interest or Their Agents: Bayer Healthcare
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Credits: 1.0 CME / 1.0 CNE
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The incidence of acquired hemophilia A occurs between approximately 1.34 and 1.48 per 1 million per year and predominantly affects older patients. Due to the subcutaneous, muscle, or gastrointestinal bleeding that presents with the disease, specialty physicians need to be aware of possible clinical presentations and treatment options. In this case-based learning activity, Craig Kessler, MD, and Mariasanta Napolitano, MD, both from the Lombardi Comprehensive Cancer Center at Georgetown University Medical Center in Washington, DC, discuss the pathogenesis and treatment of acquired hemophilia A and engage in a Q&A exchange regarding various clinical presentations and diagnoses.
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Patients with coagulation deficiencies, either congenital or acquired, may bleed spontaneously with either trauma or surgical intervention. Additionally, patients with unknown bleeding disorders not treated at hemophilia treatment centers usually seek immediate care from an emergency room. In a symposium held in conjunction with the Society for Academic Emergency Medicine Annual Meeting, Peter Kouides, MD; David Green, MD; Thomas Ortel, MD, PhD; Michael Paidas, MD; and Mark Walsh, MD, discussed several topics pertinent to EM residents who may encounter bleeding disorders. Topics included the epidemiology and clinical characteristics of adult bleeding disorders, coagulation tests and assays, taking a bleeding history, platelet function testing, and the female bleeding patient in the emergency room.
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Widespread use of anticoagulants has led to an increase in bleeding episodes seen in emergency departments. The best strategy for reversal of coaguloathy associated with warfarin-related bleeding is still under debate. In a dinner symposium held in conjunction with the Annual Meeting of the Society for Academic Emergency Medicine, W. Frank Peacock, MD; Bryan A. Cotton, MD, MPH; and David A. Garcia, MD, discussed the interpretation of current coagulation assays and their impact on clinical decisions; best practices for the rapid reversal of anticoagulant-associated intracerebral hemorrhage; and the reversal of acute traumatic coagulopathy in patients presenting to the emergency department.
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Patients with congenital bleeding disorders are at risk for poor outcomes due to the clinical challenges present during surgical procedures. In a dinner symposium held in conjunction with the 2011 ASPHO (American Society of Pediatric Hematology/Oncology) Annual Meeting, Victor S. Blanchette, MD, FRCP, Head of the Division of Hematology/Oncology at the Hospital for Sick Children; Steven W. Pipe, MD, Associate Professor of Pediatrics and Pathology at C.S. Mott Children’s Hospital, University of Michigan; and Meera B. Chitlur, MD, Assistant Professor, Division of Pediatric Hematology/Oncology at Children’s Hospital of Michigan, present on issues pertaining to the perioperative management of patients with congenital bleeding disorders. As part of their discussion, these noted experts address hemophilic and non-hemophilic inhibitors of coagulation, standard and emerging coagulation tests, and novel and experimental clotting factors.
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The goal of hemophilia therapy is to treat and prevent bleeding episodes and related complications, such as inhibitor development, by replacing the deficient clotting factor. In this learning activity, bleeding disorder expert Leonard A. Valentino, MD, assesses the benefits and risks of plasma-derived and recombinant factor replacement therapies and examines effective inhibitor prevention strategies, including prophylaxis and the avoidance of immunological danger signals.
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In this activity, Michael Recht, MD, PhD, explores the efficacy of prophylactic bypassing therapies in hemophilia A patients with inhibitors and examines evidence from comparative trials of FEIBA and rFVIIa as on-demand treatment in this patient cohort.
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What type of care is required of hemophilia A patients with inhibitors who elect to undergo orthopedic surgery? A nurse and a physical therapist discuss the preoperative and postoperative challenges such patients present to the hemophilia treatment center team. Issues addressed in this podcast include the importance of patient education, dosing of bypassing agents, calculation of factor requirements, preoperative and postoperative exercise programs, and the importance of physical therapy in the surgical patient’s rehabilitative process. An actual patient with inhibitors provides his viewpoint on the orthopedic surgery he has had and discusses his concerns, rehabilitation program, and quality-of-life issues.
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Ref No
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Description
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037
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“Management of Bleeding Episodes in Patients With Hemophilia and Inhibitors to Reduce Complications and Minimize Joint Damage”
Case-based learning activity focused on acute and long-term care of patients with hemophilia and inhibitors
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036
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“Identification, Diagnosis, and Management of Acquired Hemophilia A (AHA)”
Management of Acquired Hemophilia A (AHA)
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035
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“Prophylactic Bypassing Therapy in Pediatric Inhibitor Patients to Avoid Musculoskeletal Complications”
Prophylactic Bypassing Therapy in Pediatric Inhibitor Patients
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034
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“Acute and Chronic Pain in Hemophilia Patients”
Panel discussion on Acute and Chronic Pain in Hemophilia Patients
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033
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“Prophylactic Bypassing Therapy in Adult Hemophilia Patients Undergoing Orthopedic Surgery”
Panel discussion on prophylactic bypassing therapy in adult hemophilia patients who undergo orthopedic surgery
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032
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“Hemophilia Experts Video Summit: How We Manage the Musculoskeletal Complications of Hemophilia in Pediatric Patients”
Panel discussion on managing the musculoskeletal complications of hemophilia in pediatric patients
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031
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“Hemophilia Experts Video Summit: How We Manage the Musculoskeletal Complications of Hemophilia in Adult Patients”
Panel discussion on managing the musculoskeletal complications of hemophilia in adult patients
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030
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“Physical Therapy in Patients With Hemophilia: Helpful Tips for Clinicians: (PT Video)”
Advice for clinicians about PT in hemophilia patients
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029
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“Clinical Challenges in Your Hemophilia Treatment Center”
Learning activity addresses clinical challenges in hemophilia treatment centers
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028
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“The Aging Hemophilia Patient: Comorbidities and Management Issues”
Learning activity concerning management issues of the aging hemophilia patient
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026
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“Hemophilia Clinical Consults: Epidemiology, Clinical Course, and Management of Acquired Hemophilia A”
Interactive, case-based learning activity regarding the epidemiology, clinical presentation, and management of patients with acquired hemophilia A
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025
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“Hemophilia Clinical Consults: Hemophilic Arthropathy, Reduced Bone Density, and Preventive Strategies”
Case-based learning activity exploring preventive strategies for hemophilic arthropathy, and clinical characteristics
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024
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“Transitioning From Pediatric to Adult Hemophilia Care: Managing Lifestyle and QoL Challenges”
Learning activity concerning the transition from pediatric to adult hemophilia care
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023
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“Hemophilia Clinical Consults: Inhibitor Formation, Management, and Therapeutic Options”
Case-based, interactive learning activity exploring the natural history of inhibitors and available management and therapeutic options
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022
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“Hemophilia Clinical Consults: Therapeutic Decisions in the Perioperative Management of Patients With Hemophilia A Undergoing Surgery”
Case-based learning activity exploring surgical procedures in hemophilia A patients and factors to consider during perioperative management
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021
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“Practical Strategies for Managing Hemophilia and Preventing Inhibitor Development”
Clinical Insight featuring discussion of inhibitor prevention and treatment strategies in hemophilia
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020
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“Prophylaxis in Hemophilia Patients Without Inhibitors and Its Impact on Inhibitor Development”
Presentation on the impact of prophylaxis on inhibitor development and its use in hemophilia patients without inhibitors
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019
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“Prophylaxis in Hemophilia: Do Immunologic Danger Signals or Pharmacokinetics Hold Relevance?”
Presentation on prophylaxis and potential immunologic triggers of inhibitor development
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018
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“HTC CME NetWorkShopsTM: Current Issues and Trends in Hemophilia Care”
Learning activity concerning issues and trends in hemophilia treatment centers
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017
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“Early Prophylaxis and the Influence of Immunologic ‘Danger Signals’ on Inhibitor Development”
Learning activity concerning immunologic “danger signals” and the effects of early prophylaxis on inhibitor development
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016
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“Pathophysiology of Joint Bleeding and Synovitis: The Impact on Joint Health”
Learning activity on the impact of joint bleeding and synovitis on joint health.
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015
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“Safe Use of Radiosynovectomy for Chronic Hemophilic Synovitis”
Learning activity on the safety issues associated with radiosynovectomy for treating hemophilic synovitis
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014
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“Treatment Decisions and Clinical Outcomes in Hemophilia B Patients With Inhibitors”
Presentation on treatment decisions and clinical outcomes for inhibitor patients with FIX deficiency
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013
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“FIX Deficiency and Inhibitors: Report From the ISTH-SSC International Registry”
Learning activity concerning the ISTH-SSC International Registry and hemophilia B with inhibitors
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012
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“Clinical Challenges in Your Hemophilia Treatment Center”
Learning activity concerning clinical challenges in hemophilia treatment centers
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011
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“Management of High-Titer FVIII Inhibitors”
Learning activity on managing FVIII inhibitors in hemophilia A patients.
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010
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“Radiosynovectomy in Hemophilia”
Learning activity concerning the use of radiosynovectomy as a treatment for hemophilic synovitis.
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009
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“The Nurse Coordinator’s Perspective on Managing Hemophilia Patients With Inhibitors”
Clinical Insight featuring discussion of the nurse coordinator’s role in hemophilia care and managing hemophilia patients with inhibitors
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008
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“Perspectives in Hemophilia: Clinical Challenges and Current Issues in Managing Patients With Inhibitors”
Learning activity concerning clinical challenges in managing hemophilia patients with inhibitors.
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007
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“Expert Opinion: The Clinical Importance of Adhering to Preventive PT Regimens for Minimizing Joint Damage”
Presentation on the benefits of PT for hemophilia patients
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006
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“Hemophilia Consults: Should Patients With Inhibitors Receive Prophylaxis With Bypassing Agents?”
Learning activity concerning use of prophylactic bypassing therapy in hemophilia patients with inhibitors.
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005
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“Perspectives in Hemophilia: Clinical Challenges and Current Issues in Managing Patients With Inhibitors”
Presentation from the 2010 American Society of Pediatric/Hematology/Oncology Annual Meeting
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003
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“Elective Orthopedic Surgery in Patients With Inhibitors: The Hematologist/Orthopedic Surgeon Consult”
Expert commentary on orthopedic surgery in hemophilia A patients with inhibitors
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002
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“Elective Orthopedic Surgery in Patients With Inhibitors: Preoperative and Postoperative Care”
Preoperative and postoperative care of hemophilia A patients with inhibitors
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001
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“Elective Orthopedic Surgery in Patients With Inhibitors: Preoperative and Postoperative Care”
Preoperative and postoperative care of hemophilia A patients with inhibitors
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